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Because UCEs are conserved across disparate taxa, UCEs are also That's an extremely good question, and one to which we do not entirely know the answer (Dermitzakis et al. UCEs have been associated with gene regulation (Pennachio et al. However, gene knockouts of UCE loci in mice resulted in viable, fertile offspring (Ahituv et al.
The resulting loci are the highly conserved that we target for use as molecular markers. 2009) probes that are similar in sequence to the UCE loci we are targeting. Here's a list of UCE-related talks at various conferences.
These probe sets differ in number and composition, depending on the types of questions we are asking and the taxa with which we are working. Mc Cormack JE, Faircloth BC, Crawford NG, Gowaty PA, Brumfield RT, Glenn TC. Ultraconserved Elements Are Novel Phylogenomic Markers that Resolve Placental Mammal Phylogeny when Combined with Species Tree Analysis. Slides are available for each talk by clicking on the linked talk title.
Sue Sirotti, a 66-year-old retired teacher from western Michigan, was browsing websites when her computer screen suddenly turned blue.
A loud voice came through the speakers, telling her to call the provided number to speak to a Microsoft technician. No matter what she tried, she couldn't quiet the blaring electronic voice or get past what looked like the "blue screen of death" — a term from the early days of the Windows operating system, when a crash led to a blue error screen telling you to shut down.